Product Details

Product Information of Vipdomet Tablets

What you need to know before you take Vipdomet
Do not take Vipdomet:
• if you are allergic to alogliptin, metformin or any of the other ingredients of this medicine (listed in section 6)
• if you have had a serious allergic reaction to any other similar medicinesthat you take to control your blood sugar. Symptoms of a serious allergic reaction may include; rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. Additional symptoms may include general itching and
feeling of heat especially affecting the scalp, mouth, throat, palms of hands and soles of feet (Stevens-Johnson syndrome).
• if you have -severely reduced kidney function
• if you have uncontrolled diabetes, with, for example, severe hyperglycaemia (high blood glucose), nausea, vomiting, diarrhoea, rapid weight loss, lactate acidosis (see “Risk of lactic acidosis” below) or ketoacidosis. Ketoacidosis is a condition in which substances called  ketone bodies’ accumulate in the blood and which can lead to diabetic pre-coma. Symptoms include stomach pain, fast and deep breathing, sleepiness or your breath developing an unusual fruity smell.
• if you have a severe infection or are seriously dehydrated (have lost a lot of water from your body)
• if you recently had a heart attack or have severe circulatory problems including shock
• if you have severe breathing difficulties
• if you have liver disease
• if you drink alcohol excessively (either every day or in large quantities only from time to time)
Warnings and precautions
Talk to your doctor or pharmacist before taking Vipdomet :
• if you have type 1 diabetes (your body does not produce insulin).
• if you are taking Vipdomet with insulin or a thiazolidinedione. Your doctor may want to reduce your dose of insulin or a thiazolidinedione when you take it together with Vipdomet in order to avoid too low blood sugar (hypoglycaemia).
• if you are taking another medicine for diabetes that contains a “sulphonylurea”, you should not start taking Vipdomet.
•
• if you have or have had a disease of the pancreas.
• in case of symptoms suggestive of liver injury during Vipdomet therapy.
Contact your doctor if you encounter blistering of the skin, as it may be a sign for a condition called bullous pemphigoid. Your doctor may ask you to stop alogliptin.
Risk of lactic acidosis
Vipdomet may cause a very rare, but very serious side effect called lactic acidosis, particularly if your kidneys are not working properly. The risk of developing lactic acidosis is also increased with uncontrolled diabetes, serious infections, prolonged fasting or alcohol intake, dehydration (see further information below), liver problems and any medical conditions in which a part of the body has a
reduced supply of oxygen (such as acute severe heart disease). If any of the above apply to you, talk to your doctor for further instructions.
Stop taking Vipdomet for a short time if you have a condition that may be associated with dehydration (significant loss of body fluids) such as severe vomiting, diarrhoea, fever, exposure to heat or if you drink less fluid than normal. Talk to your doctor for further instructions.
Stop taking Vipdomet and contact a doctor or the nearest hospital immediately if you experience some of the symptoms of lactic acidosis, as this condition may lead to coma.
Lactic acidosis is a medical emergency and must be treated in a hospital. If lactic acidosis is suspected, seek medical attention from a doctor or a hospital.
Symptoms of lactic acidosis include:
• vomiting
• stomach ache (abdominal pain)
• muscle cramps
• a general feeling of not being well with severe tiredness
• difficulty in breathing
• reduced body temperature and heartbeat
If you need to have major surgery you must stop taking Vipdomet during and for some time before and after the procedure. Your doctor will decide when you must stop and when to restart your treatment with Vipdomet.
During treatment with Vipdomet, your doctor will check your kidney function at least once a year or more frequently if you are elderly and/or if have worsening kidney function
Children and adolescents
Vipdomet is not recommended for children and adolescents under 18 years due to the lack of data in these patients.
Other medicines and Vipdomet
If you need to have an injection of a contrast medium that contains iodine into your bloodstream, for example in the context of an X-ray or scan, you must stop taking Vipdomet before or at the time of
the injection. Your doctor will decide when you must stop and when to restart your treatment with Vipdomet.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. You may need more frequent blood glucose and kidney function tests, or your doctor may need to adjust the dosage of Vipdomet. It is especially important to mention the following:
• hydrocortisone and prednisolone (corticosteroids), used to treat diseases that involve inflammation like asthma and arthritis
• cimetidine, used to treat stomach problems
• bronchodilators (beta-2 agonists), used to treat asthma
• medicines which increase urine production (diuretics)
• medicines used to treat pain and inflammation (NSAID and COX-2-inhibitors, such as ibuprofen and celecoxib),
• certain medicines used for the treatment of high blood pressure (ACE inhibitors and angiotensin II receptor antagonists)
• medicines containing alcohol.
Vipdomet with alcohol
Avoid excessive alcohol intake while taking Vipdomet since this may increase the risk of lactic acidosis – see section “Warnings and precautions”.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. You should not use Vipdomet if you are pregnant.
Vipdomet is not recommended during breast-feeding since metformin passes into breast milk.
Driving and using machines
Vipdomet is not known to affect your ability to drive and use machines. Taking Vipdomet in combination with medicines called pioglitazone or insulin can cause too low blood sugar levels (hypoglycaemia), which may affect your ability to drive and use machines.

How to store Vipdomet
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month.
This medicinal product does not require any special storage conditions.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.