Side Effects

Side Effects of Cefuroxime Injection – 750mg Powder for Injection, 1 Vial

POSSIBLE SIDE EFFECTS

Like all medicines, Cefuroxime Injection can cause side effects, although not everybody gets them. Conditions you need to look out for A small number of people taking Cefuroxime get an allergic reaction or potentially serious skin reaction. Symptoms of these reactions include: • severe allergic reaction. Signs include raised and itchy rash, swelling, sometimes of the face or mouth causing difficulty in breathing. • skin rash, which may blister, and looks like small targets (central dark spot surrounded by a paler area, with a dark ring around the edge). • a widespread rash with blisters and peeling skin. (These may be signs of Stevens-Johnson syndrome or toxic epidermal necrolysis). Other symptoms you need to be aware of while taking Cefuroxime include: • fungal infections on rare occasions, medicines like Cefuroxime can cause an overgrowth of yeast (Candida) in the body which can lead to fungal infections (such as thrush). This side effect is more likely if you take Cefuroxime for a long time. • severe diarrhoea (Pseudomembranous colitis). Medicines like Cefuroxime can cause inflammation of the colon (large intestine), causing severe diarrhoea, usually with blood and mucus, stomach pain, fever. Contact a doctor or nurse immediately if you get any of these symptoms. Common side effects (may affect up to 1 in 10 people) • injection site pain, swelling and redness along a vein. Tell your doctor if any of these are troubling you. Common side effects that may show up in blood tests: • increases in substances (enzymes) produced by the liver • changes in your white blood cell count (neutropenia or eosinophilia) • low levels of red blood cells (anaemia) Uncommon side effects (may affect up to 1 in 100 people) • skin rash, itchy, bumpy rash (hives) • diarrhoea, nausea, stomach pain Tell your doctor if you get any of these. Uncommon side effects that may show up in blood tests: • low levels of white blood cells (leucopenia) • increase in bilirubin (a substance produced by the liver) • positive Coomb’s test. Other side effects Other side effects have occurred in a very small number of people but their exact frequency is unknown: • fungal infections • high temperature (fever) • allergic reactions • inflammation of the colon (large intestine), causing diarrhoea, usually with blood and mucus, stomach pain • inflammation in the kidney and blood vessels • red blood cells destroyed too quickly (haemolytic anaemia) • skin rash, which may blister, and looks like small targets (central dark spot surrounded by a paler area, with a dark ring around the edge) (erythema multiforme). Tell your doctor if you get any of these. Side effects that may show up in blood tests: • decrease in number of blood platelets (cells that help blood to clot – thrombocytopenia) • increase in levels of urea nitrogen and serum creatinine in the blood. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet.