Glucovance 500mg / 2.5mg Tablets, 30 Tablets
Control your blood sugar with ease using Glucovance 500mg / 2.5mg Tablets. This product contains a combination of glyburide and metformin, both of which are oral diabetes medicines that work together to help keep your blood sugar levels under control. Control your diabetes today with Glucovance!
Glucovance is an oral diabetes medicine that helps control blood sugar levels. It contains a combination of glyburide and metformin, both of which are oral diabetes medicines.
Glucovance is a prescription drug used to control blood glucose levels in adults with type II diabetes mellitus
Glucovance is used:
- when diet, exercise and treatment with either metformin or a sulfonylurea medicine are not enough to control your blood glucose
- in people whose blood sugar levels are already well controlled by the combination of metformin and a sulfonylurea medicine. Glucovance is to replace these two medicines.
Glucovance contains two active ingredients, metformin hydrochloride and glibenclamide.
What is type 2 diabetes?
Type 2 diabetes is a condition in which your body does not make enough insulin, and the insulin that your body produces does not work as well as it should. Your body can also make too much sugar. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems like heart disease, kidney disease, blindness, and amputation.
- Type 2 diabetes is a common condition that causes the level of sugar (glucose) in the blood to become too high.
- It can cause symptoms like excessive thirst, needing to pee a lot and tiredness. It can also increase your risk of getting serious problems with your eyes, heart and nerves.
- It\’s a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups.
- It\’s caused by problems with a chemical in the body (hormone) called insulin. It\’s often linked to being overweight or inactive, or having a family history of type 2 diabetes.
Symptoms of Type 2 Diabetes
Many people have type 2 diabetes without realising. This is because symptoms don\’t necessarily make you feel unwell.
Symptoms of type 2 diabetes include:
- peeing more than usual, particularly at night
- feeling thirsty all the time
- feeling very tired
- losing weight without trying to
- itching around your penis or vagina, or repeatedly getting thrush
- cuts or wounds taking longer to heal
- blurred vision
You\’re more at risk of developing type 2 diabetes if you:
- are over 40 – or 25 for south Asian people
- have a close relative with diabetes – such as a parent, brother or sister
- are overweight or obese
- are of south Asian, Chinese, African Caribbean or black African origin – even if you were born in the UK
Understanding your type 2 diabetes medication
Most people need medicine to control their type 2 diabetes.
The medicine helps keep your blood sugar level as normal as possible to prevent health problems. You\’ll have to take it for the rest of your life.
Diabetes usually gets worse over time, so your medicine or dose may need to change.
Adjusting your diet and being active is also necessary to keep your blood sugar level down.
How to manage your diabetes
A healthy diet and keeping active will help you manage your blood sugar level. It will also help you to control your weight and generally feel better.
YOU CAN EAT MANY TYPES OF FOODS
There\’s nothing you can\’t eat if you have type 2 diabetes, but you\’ll have to limit certain foods.
You should:
- eat a wide range of foods – including fruit, vegetables and some starchy foods like pasta
- keep sugar, fat and salt to a minimum
- eat breakfast, lunch and dinner every day – don\’t skip meals
If you need to change your diet, it might be easier to make small changes every week.
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What is the price of Glucovance 500mg / 2.5mg Tablets in Nigeria?
The price of Trajenta 5mg Tablets is N4,700
Where can you buy Glucovance 500mg / 2.5mg Tablets In Nigeria?
Glucovance 500mg / 2.5mg Tablets is available on Asset Pharmacy Lagos Nigeria, Nigeria\’s Largest Online Pharmacy
Glucovance 500mg / 2.5mg Tablets is a prescription drug that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent.
How to Use
How to take Glucovance 500mg / 2.5mg Tablets
ollow all directions given to you by your doctor and pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the pack, ask your doctor or pharmacist.
How much to take
The dose varies from person to person. Your doctor will decide the right dose for you.
People who do not respond to either metformin or a sulfonylurea medicine alone.
The usual starting dose is one Glucovance 500 mg/2.5 mg tablet once a day.
Replacing combined use of metformin and a sulfonylurea or glibenclamide medicine.
The usual starting dose is one to two tablets of Glucovance 500 mg/2.5 mg daily.
Product Details
Glucovance 500mg / 2.5mg Tablets Product Information
Before you take Glucovance
When you must not take it
Do not take Glucovance if you are allergic to the following:
metformin hydrochloride (e.g. Diabex, Diaformin, Glucophage)
glibenclamide (e.g. Daonil, Glimel)
any other sulfonylurea medicine such as gliclazide (e.g. Diamicron, Glyade), glipizide (e.g. Minidiab, Melizide), glimepiride (e.g. Amaryl, Dimirel) or any other sulfonamides (e.g. Septrin)
any of the ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath.
Do not take Glucovance if you are currently taking miconazole (Daktarin), either orally or as a mouth gel.
Taking Glucovance with miconazole may cause an excessive drop in your blood glucose level.
Do not take Glucovance if you have the following conditions:
type I diabetes mellitus also known as insulin dependent diabetes
type II diabetes that is already well controlled by diet alone
serious complications with your diabetes or or any type of metabolic acidosis such as lactic acidosis, diabetic ketoacidosis (a symptom of uncontrolled diabetes, in which substances called ketone bodies accumulate in the blood – you may notice this as an unusual fruity odour on your breath)
severe liver disease
kidney failure or severe kidney disease
dehydration (for instance due to persistent or severe diarrhoea or recurrent vomiting), severe blood loss or shock
severe infection or gangrene
certain heart or blood vessel problems, including a recent heart attack or heart failure (when the heart fails to pump blood effectively)
severe breathing difficulties
blood clots in the lung (symptoms include coughing, shortness of breath, chest pain and a fast heart rate)
pancreatitis (symptoms include severe upper stomach pain, often with nausea and vomiting) if associated with severe infection or hypoxia (lack of oxygen)
alcohol dependence or binge drinking
porphyria, an inherited disorder
glucose and galactose malabsorption syndrome or lactase deficiency.
Do not take Glucovance if you need to have major surgery or an examination such as an X-ray or a scan involving the injection of contrast medicines that contain iodine into your bloodstream.
You must stop taking Glucovance for a certain period of time before and after the examination or the surgery. Your doctor will decide whether you need any other treatment for this time. It is important that you follow your doctor’s instructions precisely.
Do not take Glucovance if you are pregnant.
Insulin is more suitable for controlling blood glucose during pregnancy. Your doctor will replace Glucovance with insulin while you are pregnant.
Do not take Glucovance if you are breastfeeding.
Since it is not known whether Glucovance passes into breast milk, Glucovance is not recommended while you are breast-feeding.
Do not take Glucovance after the expiry date (EXP.) printed on the pack has passed.
If you take this medicine after the expiry date, it may not work as well.
Do not take Glucovance if the packaging shows signs of tampering or the tablets do not look quite right.
Do not give Glucovance to children or adolescents.
The safety and effectiveness of Glucovance have not been established in children or adolescents.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Before you start to take it
Tell your doctor if you have allergies to:
any other medicines
any other substances, such as foods, preservatives or dyes.
Tell your doctor if you have, or have had, any medical conditions, especially the following:
kidney problems
liver problems
hormone problems with the thyroid, pituitary or adrenal gland
heart or blood vessel problems including heart failure.
Your doctor may want to take special care if you have any of these conditions.
Tell your doctor if you:
drink alcohol
do not eat regular meals, are fasting or have changed your diet
do a lot of exercise
are ill or feeling unwell.
Alcohol, diet, exercise and your general health all strongly affect the control of your diabetes.
If you have not told your doctor about any of the above, tell him/her before you start taking Glucovance.
Taking other medicines
Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Some medicines may be affected by Glucovance, or may affect how well it works. These include:
other medicines containing metformin or glibenclamide
other medicines used to treat diabetes
iodinated contrast agents (dyes)
medicines that contain alcohol, such as cough and cold syrups
diuretics, also called fluid tablets
certain antifungal medicines, such as miconazole (Daktarin Oral Gel) and fluconazole (Diflucan)
certain antibiotics including medicines used to treat tuberculosis
medicines used to treat high blood pressure and heart conditions (clonidine, reserpine, guanethidine, sympathicomimetics, beta-blockers, calcium channel blockers and ACE inhibitors)
disopyramide (Rhythmodan), a medicine used to treat an irregular heart beat
non-steroidal anti-inflammatory drugs (NSAIDS), medicines used to relieve pain, swelling and other symptoms of inflammation including arthritis, such as aspirin and phenylbutazone
desmopressin (Minirin), a medicine used to treat diabetes insipidus, a condition causing large amounts of urine to be produced
danazol (Danocrine, Azol), a medicine used to treat endometriosis
bosentan, a medicine used to treat pulmonary hypertension
phenytoin (Dilantin), a medicine used to treat epilepsy (fits or seizures)
medicines used to treat depression such as fluoxetine (e.g. Prozac, Lovan) and monoamine oxidase inhibitors (MAOIs)
medicines used to treat schizophrenia and mental illnesses, such as chlorpromazine (Largactil) and phenothiazines
corticosteroids, such as prednisone (Panafcort, Sone) and cortisone (Cortate)
medicine used to stimulate the adrenocortical hormones, such as tetracosactide (tetracosactrin)
anabolic steroids
oestrogens and progestagens in hormone replacement therapy and oral contraceptives
thyroid hormones, such as thyroxine (e.g. Oroxine, Eutrosig)
some medicines used for asthma
medicines used to treat for ulcers and reflux, such as cimetidine (e.g. Tagamet, Magicul) and ranitidine (e.g. Zantac, Rani 2)
medicines used to prevent or to treat blood clots such as warfarin (Coumadin, Marevan), heparin or sulphinpyrazone
medicines used to lower lipids, such as bezafibrate, clofibrate, gemfibrozil (Lopid) and nicotinic acid
pentoxifylline (oxpentifylline)injection, a medicine used to treat blood vessel problems
certain medicines used to treat cancer
certain medicines used to treat gout such as probenecid (Pro-cid)
acetazolamide (Diamox), a medicine used to treat glaucoma
certain weight reducing medicines
large doses of laxatives.
medicines that are substrates/ inhibitors of organic cation transporters – OCT 1 such as verapamil; OCT 2 such as dolutegravir, crizotinib, olaparib, daclatasvir or vandetanib
medicines that are inducers of OCT 1 such as rifampicin
medicines that may increase the risk of lactic acidosis when concomitantly used with metformin hydrochloride such as topiramate and other carbonic anhydrase inhibitors, such as zonisamide, acetazolamide or dicchlorphenamide.
These medicines may be affected by Glucovance or may affect how well it works. You may need different amounts of your medicines or you may need to take different medicines.
Your doctor can tell you what to do if you are taking any of these medicines.
If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Glucovance.
Side Effects
Side Effects of Glucovance 500mg / 2.5mg Tablets
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Glucovance.
Glucovance helps most people with type II diabetes but it may have unwanted side effects in some people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
If you are an elderly person over 65 years of age, report any side effects promptly to your doctor.
You may have an increased chance of getting side effects.
Do not be alarmed by this list of possible side effects.
You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
signs of hypoglycaemia which may include weakness, trembling or shaking, sweating, light headedness, headache, dizziness, irritability and tearfulness
stomach upset including nausea (feeling sick), vomiting and indigestion
pressure on the stomach or feeling of fullness
diarrhoea
loss of appetite
taste disturbance
mild skin rash
transient visual disturbances due to a decrease of blood glucose levels
flushing, headache, breathing difficulties, rapid heart beat, stomach pains or feel sick and vomit if you drink alcohol while taking Glucovance.
The above list includes some of the milder side effects of Glucovance.
Tell your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following:
skin reactions including severe skin rash, itching or hives
symptoms of sunburn such as redness, itching or blistering, which may occur more quickly than normal
bleeding or bruising more easily than normal, reddish or purplish blotches under the skin
symptoms of liver disease such as yellowing of the eyes or skin (jaundice) and dark coloured urine
frequent signs of infection, such as fever, chills, sore throat or mouth ulcers.
The side effects listed above are serious and require urgent medical attention or hospitalization.
Prescription Product
This product requires a prescription from your Doctor.
Please follow the instruction received from the pharmacy on how to forward your prescription to the pharmacy after you have paid for the medicine.
A prescription drug is a pharmaceutical medication that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent
Delivery
Delievry time are estimates. Can vary due to the time of day you order.
Delivery time estimate are subject to the courier company.
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