Description
Lamotrigine 25mg Tablets, 56 Tablets
Lamotrigine 25mg is used to treat two conditions – epilepsy and bipolar disorder. It is an antiepileptic medicine that belongs to a group of medicines called sodium channel blockers. Lamotrigine works by stabilizing electrical activity in the brain. It is thought to work by preventing the release of a neurotransmitter called glutamate. By blocking glutamate, lamotrigine reduces severity and frequency of seizures and can also help to stabilize mood in people with bipolar disorder. Lamotrigine is available as tablets and oral suspension.
Lamotrigine 25mg is used to treat:
-Epilepsy: Lamotrigine is indicated for use as adjunctive therapy in adults and children over 2 years of age with partial-onset seizures or primary generalized tonic-clonic seizures.
-Bipolar disorder: Lamotrigine is indicated for use as adjunctive therapy in adults 18 years of age or older with bipolar I disorder to delay the time to occurrence of mood episodes (depression, mania, hypomania, mixed episodes) in patients treated for acute mood episodes with standard therapy.
Can someone who is pregnant or breastfeeding use Lamotrigine 25mg Tablets?
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine
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What is the price of Lamotrigine 25mg Tablets in Nigeria?
The price of Lamotrigine 25mg Tablets is N8,000
Where can you buy Lamotrigine 25mg Tablets In Nigeria?
You can Buy Lamotrigine 25mg Tablets at Asset Pharmacy Lagos Nigeria, Nigeria’s Largest Online Pharmacy.
Lamotrigine 25mg Tablets is not available to buy over the counter. You need a prescription to buy Lamotrigine 25mg Tablets
Lamotrigine 25mg Tablets is a prescription drug that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent.
You will be required to send Asset Pharmacy your prescription
How to Use
How to take Lamotrigine Tablets
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you’re not sure.
How much Lamotrigine Tablets to take
It may take a while to find the best dose of Lamotrigine Tablets for you.
The dose you take will depend on:
- your age
- whether you are taking Lamotrigine Tablets with other medicines
- whether you have any kidney or liver problems
Your doctor will prescribe a low dose to start, and gradually increase the dose over a few weeks until you reach a dose that works for you (called the effective dose).
Never take more Lamotrigine Tablets than your doctor tells you to.
The recommended effective dose of Lamotrigine Tablets for adults and children aged 13 years or over is between 100 mg and 400 mg each day.
For children aged 2 to 12 years, the effective dose depends on their body weight – usually, it’s between 1 mg and 15 mg for each kilogram of the child’s weight, up to a maximum maintenance dose of 200 mg daily.
Lamotrigine is not recommended for children aged under 2 years.
How to take your dose of Lamotrigine Tablets
Take your dose of Lamotrigine Tablets once or twice a day, as your doctor advises. It can be taken with or without food.
Your doctor may also advise you to start or stop taking other medicines, depending on what condition you’re being treated for and the way you respond to treatment.
- Swallow your tablets whole.
If you need to halve your tablets ( to take half the dose for the 25 and 100mg strengths or for ease of swallowing for the 25, 100 and 200mg strengths), then swallow tablet halves whole.
Remember not to chew or crush them. (see leaflet)
- Always take the full dose that your doctor has prescribed. Never take only part of a tablet.
Product Details
What you need to know before you take Lamotrigine Tablets
DO NOT take Lamotrigine Tablets • if you are allergic to lamotrigine or any of the other ingredients of this medicine (listed in section 6). Lamotrigine 100 mg tablets • if you are allergic to lamotrigine, sunset yellow aluminium lake or any of the other ingredients of this medicine (listed in section 6). If this applies to you: → Tell your doctor, and don’t take Lamotrigine Tablets Warnings and precautions Talk to your doctor or pharmacist before taking Lamotrigine • if you have any kidney problems • if you have ever developed a rash after taking lamotrigine or other medicines for bipolar disorder or epilepsy; or if you experience a rash or sunburn after taking lamotrigine and having been exposed to sun or artificial light (e.g. solarium). Your doctor will check your treatment and may advise you to avoid sunlight or protect yourself against the sun (e.g., use of a sunscreen and/or to wear protective clothing). • if you have ever developed meningitis after taking lamotrigine (read the description of these symptoms in Section 4 of this leaflet: Rare side effects) • if you are already taking medicine that contains lamotrigine. If any of these applies to you: → Tell your doctor, who may decide to lower the dose, or that Lamotrigine Tablets is not suitable for you. Brugada syndrome Brugada syndrome is a genetic disease that results in abnormal electrical activity within the heart. ECG abnormalities which may lead to arrhythmias (abnormal heart rhythm) can be triggered by lamotrigine. Talk to your doctor, if you have this condition. Haemophagocytic lymphohistiocytosis (HLH) There have been reports of a rare but very serious immune system reaction, in patients taking lamotrigine. Contact your doctor or pharmacist immediately if you experience any of the following symptoms while taking lamotrigine: fever, rash, neurological symptoms (e.g. shaking or tremor, confusional state, disturbances of brain function). Important information about potentially serious reactions A small number of people taking Lamotrigine get an allergic reaction or potentially life-threatening skin reaction, which may develop into more serious problems if they are not treated. These can include Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS). You need to know the symptoms to look out for while you are taking lamotrigine. → Read the description of these symptoms in section 4 of this leaflet under ‘Potentially life-threatening reactions: get a doctor’s help straight away’. Thoughts of harming yourself or suicide Anti-epileptic medicines are used to treat several conditions, including epilepsy and bipolar disorder. People with bipolar disorder can sometimes have thoughts of harming themselves or committing suicide. If you have bipolar disorder, you may be more likely to think like this: • when you first start treatment • if you have previously had thoughts about harming yourself or about suicide • if you are under 25 years old. If you have distressing thoughts or experiences, or if you notice that you feel worse or develop new symptoms while you’re taking Lamotrigine: → See a doctor as soon as possible or go to the nearest hospital for help. You may find it helpful to tell a family member, caregiver or close friend that you can become depressed or have significant changes in mood, and ask them to read this leaflet. You might ask them to tell you if they are worried about your depression or other changes in your behaviour. A small number of people being treated with anti-epileptics such as Lamotrigine Tablets have also had thoughts of harming or killing themselves. If at any time you have these thoughts, immediately contact your doctor. If you’re taking Lamotrigine Tablets for epilepsy The seizures in some types of epilepsy may occasionally become worse or happen more often while you’re taking Lamotrigine Tablets. Some patients may experience severe seizures, which may cause serious health problems. If your seizures happen more often, or if you experience a severe seizure while you’re taking Lamotrigine Tablets: → See a doctor as soon as possible. Lamotrigine Tablets should not be given to people aged under 18 years to treat bipolar disorder. Medicines to treat depression and other mental health problems increase the risk of suicidal thoughts and behaviour in children and adolescents aged under 18 years. Other medicines and Lamotrigine Tablets Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines – including herbal medicines or other medicines you bought without a prescription. Your doctor need to know if you are taking other medicines to treat epilepsy or mental health problems. This is to make sure you take the correct dose of Lamotrigine. These medicines include: • oxcarbazepine, felbamate, gabapentin, levetiracetam, pregabalin, topiramate or zonisamide, used to treat epilepsy • lithium,olanzapine or aripiprazole, used to treat mental health problems • bupropion, used to treat mental health problems or to stop smoking → Tell your doctor if you are taking any of these. Some medicines interact with Lamotrigine Tablets or make it more likely that people will have side effects. These include: • valproate, used to treat epilepsy and mental health problems • carbamazepine, used to treat epilepsy and mental health problems • phenytoin, primidone or phenobarbitone, used to treat epilepsy • risperidone, used to treat mental health problems • rifampicin, which is an antibiotic • medicines used to treat Human Immunodeficiency Virus (HIV) infection (a combination of lopinavir and ritonavir or atazanavir and ritonavir) • hormonal contraceptives, such as the Pill (see below). → Tell your doctor if you are taking any of these, or if you start or stop taking any. Hormonal contraceptives (such as the Pill) can affect the way Lamotrigine Tablets works Your doctor may recommend that you use a particular type of hormonal contraceptive, or another method of contraception, such as condoms, a cap or a coil. If you are using a hormonal contraceptive like the Pill, your doctor may take samples of your blood to check the level of Lamotrigine Tablets. If you are using a hormonal contraceptive, or if you plan to start using one: → Talk to your doctor, who will discuss suitable methods of contraception with you. Lamotrigine Tablets can also affect the way hormonal contraceptives work, although it’s unlikely to make them less effective. If you are using a hormonal contraceptive, and you notice any changes in your menstrual pattern, such as breakthrough bleeding or spotting between periods: → Tell your doctor. These may be signs that Lamotrigine Tablets is affecting the way your contraceptive is working. Pregnancy and breast-feeding If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine • You should not stop treatment without discussing this with your doctor. This is particularly important if you have epilepsy. • Pregnancy may alter the effectiveness of Lamotrigine, so you may need blood tests and your dose of Lamotrigine may be adjusted. • There may be a small increased risk of birth defects, including a cleft lip or cleft palate, if Lamotrigine is taken during the first 3 months of pregnancy. • Your doctor may advise you to take extra folic acid if you’re planning to become pregnant and while you’re pregnant. → If you are breast-feeding or planning to breast-feed ask your doctor or pharmacist for advice before taking this medicine. The active ingredient of Lamotrigine Tablets passes into breast milk and may affect your baby. Your doctor will discuss the risks and benefits of breast-feeding while you’re taking Lamotrigine Tablets, and will check your baby from time to time, whether drowsiness, rash or poor weight gain occurs if you decide to breast-feed. Inform your doctor if you observe any of these symptoms in your baby. Driving and using machines Lamotrigine Tablets can cause dizziness and double vision. → Don’t drive or operate machines unless you are sure you’re not affected. If you have epilepsy, talk to your doctor about driving and using machines. Lamotrigine Tablets tablets contains lactose If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product. Lamotrigine Tablets 100 mg tablets contain sunset yellow aluminium lake, which may cause allergic reactions. Lamotrigine tablets contains Sodium This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium free
Side Effects
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. Potentially life-threatening reactions: get a doctor’s help straight away A small number of people taking Lamotrigine Tablets get an allergic reaction or potentially life-threatening skin reaction, which may develop into more serious problems if they are not treated. These symptoms are more likely to happen during the first few months of treatment with Lamotrigine, especially if the starting dose is too high or if the dose increased too quickly, or if Lamotrigine is taken with another medicine called valproate. Some of the symptoms are more common in children, so parents should be especially careful to watch out for them. Symptoms of these reactions include: • skin rashes or redness, which may develop into lifethreatening skin reactions including widespread rash with blisters and peeling skin, particularly occurring around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome), extensive peeling of the skin (more than 30% of the body surface – toxic epidermal necrolysis) or extended rashes with liver, blood and other body organs involvement (Drug Reaction with Eosinophilia and Systemic Symptoms which is also known as DRESS hypersensitivity syndrome) • ulcers in the mouth, throat, nose or genitals • a sore mouth or red or swollen eyes (conjunctivitis) • a high temperature (fever), flu-like symptoms or drowsiness • swelling around your face, or swollen glands in your neck, armpit or groin • unexpected bleeding or bruising, or the fingers turning blue • a sore throat, or more infections (such as colds) than usual. • increased levels of liver enzymes seen in blood tests • an increase in a type of white blood cell (eosinophils) • enlarged lymph nodes • involvement of the organs of the body including liver and kidneys. In many cases, these symptoms will be signs of less serious side effects. But you must be aware that they are potentially lifethreatening and can develop into more serious problems, such as organ failure, if they are not treated. If you notice any of these symptoms: → Contact a doctor immediately. Your doctor may decide to carry out tests on your liver, kidneys or blood, and may tell you to stop taking Lamotrigine Tablets. In case you have developed Stevens-Johnson syndrome or toxic epidermal necrolysis your doctor will tell you that you must never use lamotrigine again. Haemophagocytic lymphohistiocytosis (HLH) (see section 2: What you need to know before you take Lamotrigine) Very common (may affect more than 1 in 10 people): • headache • skin rash. Common (may affect up to 1 in 10 people): • aggression or irritability • feeling sleepy or drowsy • feeling dizzy • shaking or tremors • difficulty in sleeping (insomnia) • feeling agitated • diarrhoea • dry mouth • feeling sick (nausea) or being sick (vomiting) • feeling tired • pain in your back or joints, or elsewhere. Uncommon (may affect up to 1 in 100 people): • clumsiness and lack of co-ordination (ataxia) • double vision or blurred vision • unusual hair loss or thinning (alopecia) • skin rash or sunburn after exposure to sun or artificial light (photosensitivity). Rare (may affect up to 1 in 1,000 people): • a life-threatening skin reaction (Stevens-Johnson syndrome): (see also the information at the beginning of Section 4). • a group of symptoms together including: • fever, nausea, vomiting, headache, stiff neck and extreme sensitivity to bright light. • This may be caused by an inflammation of the membranes that cover the brain and spinal cord • (meningitis). These symptoms usually disappear once treatment is stopped however if the symptoms continue or get worse contact your doctor. • rapid, uncontrollable eye movements (nystagmus) • itchy eyes, with discharge and crusty eyelids (conjunctivitis). Very rare( may affect up to 1 in 10,000 people): • a life-threatening skin reaction (toxic epidermal necrolysis): (see also the information at the beginning of Section 4). • Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): (see also the information at the beginning of Section 4) • a high temperature (fever): (see also the information at the beginning of Section 4) • swelling around the face (oedema) or swollen glands in the neck, armpit or groin (lymphadenopathy): (see also the information at the beginning of Section 4) • changes in liver function, which will show up in blood tests, or liver failure: (see also the information at the beginning of Section 4) • a serious disorder of blood clotting, which can cause unexpected bleeding or bruising (disseminated intravascular coagulation): (see also the information at the beginning of Section 4) • changes which may show up in blood tests – including reduced numbers of red blood cells (anaemia), reduced numbers of white blood cells (leucopenia, neutropenia, agranulocytosis), reduced numbers of platelets (thrombocytopenia), reduced numbers of all these types of cell (pancytopenia), and a disorder of the bone marrow called aplastic anaemia • hallucinations (‘seeing’ or ‘hearing’ things that aren’t really there) • confusion • feeling ‘wobbly’ or unsteady when you move about • uncontrollable body movements (tics), uncontrollable muscle spasms affecting the eyes, head and torso (choreoathetosis), or other unusual body movements such as jerking, shaking or stiffness • in people who already have epilepsy, seizures happening more often • in people who already have Parkinson’s disease, worsening of the symptoms. • lupus-like reaction (symptoms may include: back or joint pain which sometimes may be accompanied by fever and/or general ill-health). • Haemophagocytic lymphohistiocytosis (HLH) (see section 2 What you need to know before you take lamotrigine). Other side effects Other side effects have occurred in a small number of people but their exact frequency is unknown: • There have been reports of bone disorders including osteopenia and osteoporosis (thinning of the bone) and fractures. Check with your doctor or pharmacist if you are on long-term antiepileptic medication, have a history of osteoporosis, or take steroids. • inflammation of the kidney (tubulointerstitial nephritis) or inflammation of both the kidney and the eye (tubulointerstitial nephritis and uveitis syndrome) • Nightmares. • Lower immunity because of lower levels of antibodies called immunoglobulins in the blood which help protect against infection. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet
Ingredients
What Lamotrigine Tablets contains
– The active substance is lamotrigine.
Each tablet contains 25 mg lamotrigine
The other ingredients are Cellulose microcrystalline, lactose monohydrate, indigo carmine aluminium lake (E132) (For 200 mg only), sunset yellow aluminium lake (E110) (For 100 mg only), sodium starch glycolate (Type A), magnesium stearate, povidone (K30)
How to store
How to store Lamotrigine Tablets
Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date, which is stated on the blister/label of the bottle and the carton after the EXP. The expiry date refers to the last day of that month. This medicinal product does not require any special storage conditions. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment
Prescription Product
This product requires a prescription from your Doctor.
Please follow the instruction received from the pharmacy on how to forward your prescription to the pharmacy after you have paid for the medicine.
A prescription drug is a pharmaceutical medication that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent
Delivery
Delievry time are estimates. Can vary due to the time of day you order.
Delivery time estimate are subject to the courier company.
Shipping to Lagos cost starts from N1850 Next day delivery
Shipping to Rest Of Nigeria – 2-3 days cost starts from N2000
Shipping to Rest of Africa – 5-7 working days Cost starts from N12000
Shipping to Europe 7 – 14 working days Cost srats from N18000
Shipping to Rest of the world – 7 – 14 days Cost starts from N18000
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