Do not take this medicine if:

• The person taking the medicine is under 2 years of age
• You are allergic (hypersensitive) to promethazine hydrochloride or any of the other ingredients of Rophegan Syrup (listed in Section 6 below)
  The signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue
• You are taking a medicine for depression called a monoamine oxidase inhibitor (MAOI). Also do not take Phenergan Elixir if you have stopped taking one of these MAOI medicines within the last 14 days. If you are not sure ask your doctor or pharmacist (see “Taking other medicines” section below)
• The person is unconscious (in a coma) or suffers from severe dizziness, drowsiness or headache

Do not take this medicine if any of the above applies to you.

If you are not sure, talk to your doctor or pharmacist before taking Rophegan Syrup.

Warnings and precautions

Check with your doctor or pharmacist before taking your medicine if:

• You have difficulty breathing, wheezing,tightness in the chest (asthma) or an infection in your lungs (bronchitis)
• You have epilepsy
• You have any serious heart problems
• You have liver or kidney problems
• You have a stomach blockage or difficulty passing water
• You have hearing problems
• You have increased pressure in the eye (narrow angle glaucoma)
• You have had something called Reye’s Syndrome or possible Reye’s Syndrome – signs include being sick and confused following a viral illness
• You have diabetes. This medicine contains hydrogenated glucose syrup (see ‘Important information about some of the ingredients of Phenergan Elixir’ below)

If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Phenergan Elixir.

Other medicines and Rophegan Syrup

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines you can buy without prescription, including herbal medicines. This is because Rophegan Syrup can affect the way some medicines work. Also some medicines can affect the way Phenergan Elixir works.

Do not take this medicine, and tell your doctor, if you are taking or have taken the following in the last 2 weeks:

• Some medicines for depression called monoamine oxidase inhibitors (MAOIs). If you are not sure ask your doctor or pharmacist

Tell your doctor or pharmacist if you are taking any of the following:

• Anticholinergic medicines – includes some medicines used for irritable bowel syndrome, asthma or weak bladder. These can increase the risk of dizziness, dry mouth and blurred eyesight
• Medicines for depression (such as amitriptyline)
• Medicines to help you to sleep or feel more relaxed (such as diazepam or zolpidem)
• Medicines such as aspirin (for arthritis and pain in your joints). Phenergan Elixir may hide the side effects of these medicines

Rophegan Syrup with food and drink

Do not drink alcohol while you are taking Rophegan Syrup. This is because it can affect the way the medicine works.

Pregnancy and breast-feeding

Talk to your doctor or pharmacist before taking this medicine if you are pregnant, might become pregnant, or think you may be pregnant. Rophegan Syrup should not be taken in the 2 weeks before birth.

You should not take Phenergan Elixir if you are breast-feeding. This is because small amounts may pass into mothers’ milk. This can be harmful to your baby.

If you are breast-feeding or planning to breast-feed, talk to your doctor or pharmacist before taking any medicine.

Driving and using machines

You may feel drowsy or sleepy while taking this medicine or in the morning after taking this medicine. If this happens, do not drive or use any tools or machines.

Rophegan Syrup contains:

• Hydrogenated glucose syrup (maltitol liquid). This is a type of carbohydrate which the body will convert into small amounts of sugar. The maximum 25ml single dose of Phenergan Elixir is equivalent to approximately 5 grams of sugar, or one teaspoon of sugar/ sugar lump. Taking this amount of Phenergan Elixir is unlikely to affect the control of your diabetes or require you to increase your diabetes medication. If you have been told by your doctor that you cannot tolerate or digest some sugars (have an intolerance to some sugars), talk to your doctor before taking this medicine. Hydrogenated glucose syrup may have a mild laxative effect. The calorific value of hydrogenated glucose syrup is 2.3kcal/g. A 5ml dose (one teaspoon) contains approximately 10kcal.
• Sodium sulphite and sodium metabisulphite. These may rarely cause severe allergic (hypersensitivity) reactions and difficulty breathing, wheezing and tightness in the chest (bronchospasm)
• Sodium. It contains 37mg sodium per dose (5ml). Take this into account if you are on a controlled sodium diet